Metagenics® MethylCare™ – Methylation Support Formula (120 Capsules)

Serving size: 2 Capsules† | Amount Per Serving
Riboflavin … 1.6 mg
Vitamin B6 … 25 mg (as pyridoxine HCl)
Folate … 1,330 mcg DFE (as calcium L-5-methyltetrahydrofolate)††
Vitamin B12 … 1,000 mcg (as methylcobalamin)
Zinc … 1.5 mg (as zinc citrate)
Manganese … 0.4 mg (as manganese citrate)
Molybdenum … 15 mcg (as molybdenum glycinate)
N-Acetyl-L-Cysteine … 600 mg*
Betaine HCl … 500 mg*

Other Ingredients: Capsule (hydroxypropylmethylcellulose), silicified microcrystalline cellulose, stearic acid (vegetable), magnesium stearate (vegetable), and silica. This product is non-GMO and gluten-free. ††As Metafolin®. Metafolin® is a registered trademark of Merck KGaA, Darmstadt Germany. †Vegetarian capsules.

Storage: Keep tightly closed in a cool, dry place.

Advanced Methylation Support for Brain, Heart & Cellular Health

Metagenics® MethylCare™ is a clinician-formulated supplement designed to support healthy methylation — one of the most critical biochemical processes in the human body. Occurring billions of times per second in every cell, methylation influences everything from DNA synthesis and repair to neurotransmitter production, cardiovascular health, and detoxification.

Formulated with active, bioavailable forms of key B vitamins, MethylCare™ is designed for individuals who need targeted methylation support, including those with MTHFR gene variants that impair the body's ability to convert standard folate into its active form.

Key Benefits

• Supports Healthy Methylation: Provides the essential cofactors needed for optimal methylation cycle function throughout the body
• Cardiovascular Health: Helps maintain homocysteine levels already within normal range — elevated homocysteine is a key cardiovascular risk marker
• Brain & Cognitive Support: Methylation is essential for neurotransmitter synthesis (serotonin, dopamine, norepinephrine) — supporting mood, focus, and cognitive function
• DNA Synthesis & Repair: Supports the methylation reactions critical for healthy DNA replication and repair
• Energy Metabolism: Active B vitamins support mitochondrial energy production and reduce fatigue
• Detoxification Support: Methylation is a key phase II liver detoxification pathway, supporting the body's ability to process and eliminate toxins

Key Ingredients

• Methylfolate (5-MTHF) as calcium L-5-methyltetrahydrofolate (Metafolin®): The biologically active form of folate — bypasses the MTHFR enzyme conversion step for direct cellular utilization
• Methylcobalamin (B12): The active, neurologically bioavailable form of Vitamin B12, superior to cyanocobalamin for methylation support
• Pyridoxine HCl (B6): Vitamin B6 essential for homocysteine metabolism and neurotransmitter synthesis
• Riboflavin (B2): Supports MTHFR enzyme function and the methylation cycle
• Betaine HCl (TMG): Supports the BHMT methylation pathway as an alternative route for homocysteine remethylation
• N-Acetyl-L-Cysteine (NAC): Precursor to glutathione, supporting antioxidant defense and detoxification

Who Benefits Most from MethylCare™

• Individuals with MTHFR gene variants (C677T or A1298C) who cannot efficiently convert folic acid to active folate
• Those with elevated homocysteine levels seeking nutritional support
• Patients supporting cardiovascular, neurological, or cognitive health
• Individuals under high stress, which depletes methyl donors rapidly
• Those supporting liver detoxification and overall metabolic health

Why KHANG PHARMACY Recommends This

Methylation dysfunction is far more common than most people realize — studies suggest up to 40% of the population carries MTHFR variants that impair methylation efficiency. Yet standard multivitamins contain folic acid, which these individuals cannot properly utilize.

We recommend Metagenics® MethylCare™ because:

• Clinician-Grade Formulation: Metagenics products are developed by healthcare professionals and sold exclusively through licensed practitioners — a mark of clinical credibility
• Active B Vitamin Forms: Methylfolate and methylcobalamin are in their active forms; B6 and B2 are included as pyridoxine HCl and riboflavin respectively, as labeled
• Comprehensive Methylation Coverage: Addresses multiple methylation pathways simultaneously for complete support
• Trusted by Healthcare Professionals: Metagenics is one of the most respected names in practitioner-grade nutritional supplements worldwide

For patients with MTHFR variants, cardiovascular concerns, or neurological health goals, MethylCare™ represents the clinical standard in methylation support.

Suggested Use

Take as directed by your healthcare professional. Typically 2 capsules daily with food. Consult your KHANG PHARMACY pharmacist for personalized guidance.

Allergy Warning: Do not use if you are allergic to any of the ingredients listed above. Discontinue use immediately and seek emergency medical attention if you experience symptoms of an allergic reaction, including rash, hives, swelling, or difficulty breathing.

Caution: If pregnant or nursing, or taking medications, please consult your healthcare practitioner before use. Keep out of the reach of children.

Quality Assurance

Manufactured by Metagenics® in a cGMP-certified facility. Non-GMO. Gluten-free. 120 capsules per bottle. Store in a cool, dry place.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before use, especially if pregnant, nursing, or taking medications.