Why Your Gut Needs Nighttime Support: UltraFlora® Night Rest & Digest Postbiotic
Most people think about gut health during the day — after a heavy meal, when bloating strikes, or when digestion feels off. But here's what the science is telling us: nighttime may be the most important window for digestive recovery. And a new category of supplement — postbiotics — is changing how we support that process.
The Gut-Sleep Connection You Did Not Know You Had
Your gut and your brain are in constant communication through the gut-brain axis — a signaling network that connects your digestive system to your central nervous system. When digestion is incomplete or your gut microbiome is out of balance, that communication can trigger discomfort, restlessness, and disrupted sleep. Supporting digestion at night helps keep that signaling pathway calm, so your body can focus on rest rather than processing a backlog. UltraFlora® Night Rest & Digest is formulated specifically to support that connection.*
Why Nighttime Is the Right Time
Your body shifts into rest and digest mode at night, meaning your parasympathetic nervous system prioritizes internal repair and digestion over external activity. Taking digestive enzymes before bed puts support where your body is already focused — helping break down food from your evening meal so you wake up feeling light and comfortable rather than heavy or bloated.* Nighttime bloating is often caused by undigested food fermenting in the gut, producing gas that builds up while you sleep. Digestive enzymes help break down proteins, fats, and carbohydrates more completely before they reach the colon — reducing the fuel available for gas-producing bacteria.*
What Is a Postbiotic?
You have likely heard of probiotics (live beneficial bacteria) and prebiotics (the fiber that feeds them). Postbiotics are the next evolution: bioactive compounds produced when probiotics break down and ferment food in your gut. Unlike probiotics, postbiotics are stable, shelf-ready compounds that support gut barrier function, reduce digestive discomfort, and help maintain a balanced gut environment — without needing to rely on live cultures alone.*
Introducing UltraFlora® Night Rest & Digest Postbiotic by Metagenics
UltraFlora® Night Rest & Digest Postbiotic is a dual-action nighttime formula that combines clinically studied digestive enzymes, a postbiotic strain, and targeted botanicals to support your gut and sleep from multiple angles — taken before bed, working while you sleep. No melatonin. No antacids.
The Science Inside: Key Ingredients
-
Asafin® (Asafetida oleo-gum-resin extract) — 250 mg
An extract from the Hing plant shown to reduce bloating, burning, and digestive discomfort.* -
Poolzyme® (Proprietary Enzyme Blend) — 200 mg
A precision blend of 5 digestive enzymes — Lactase, Protease, Amylase, Lipase, and Cellulase — that work together to break down dairy, proteins, starches, fats, and plant fibers for easier, more complete digestion.* -
Milk Thistle (Silybum marianum) seed extract — 80 mg
A botanical extract to help support liver function and the body's natural detox processes.* -
Heat-treated Bifidobacterium longum subsp. longum CECT7347 (ES1) — 25 mg
A postbiotic strain (heat-treated, not a live culture) that supports a healthy microbiome and the gut-brain connection.* The heat-treatment process is what makes this a true postbiotic — stable, shelf-ready, and effective without requiring refrigeration.
Together, these ingredients support comfortable overnight digestion, relief from occasional indigestion, and better sleep through the gut-brain connection.*
Supplement Facts
Serving Size: 1 Capsule | Servings per Container: 30
| Ingredient | Amount Per Serving |
|---|---|
| Asafetida oleo-gum-resin extract (Asafin®) | 250 mg |
| Proprietary Enzyme Blend (Lactase, Protease, Amylase, Lipase & Cellulase) (Poolzyme®) | 200 mg |
| Milk Thistle (Silybum marianum) seed extract | 80 mg |
| Heat-treated Bifidobacterium longum subsp. longum CECT7347 (ES1) | 25 mg |
**Daily Value not established.
Other Ingredients: Capsule [hydroxypropylmethylcellulose, water, sorbitol, silicon dioxide, and sodium copper chlorophyllin (color)], microcrystalline cellulose, magnesium stearate (vegetable), and silicon dioxide.
Key Benefits
- Relieves 5 common indigestion symptoms: bloating, fullness, belching, burning, and post-meal discomfort*
- Supports the gut-brain axis for more restful, restorative sleep*
- Breaks the gut-sleep cycle by addressing digestive distress at its source — overnight*
- 5-enzyme blend breaks down dairy, proteins, starches, fats, and plant fibers*
- Postbiotic strain (heat-treated, stable) supports microbiome balance without live cultures*
- Milk thistle supports liver function and overnight detox processes*
Who Is This For?
UltraFlora® Night Rest & Digest is ideal for adults who experience bloating, fullness, or discomfort after dinner, have trouble falling or staying asleep due to digestive issues, want to support gut health without stimulants or sedatives, or are looking for a clean, evidence-based supplement from a trusted clinical brand.
Third-Party Tested. Practitioner Trusted.
For over 40 years, Metagenics® has led innovation in health supplements, exceeding industry standards for transparency and accountability. Their commitment: what is on the label is what is in the bottle. That is why they are trusted by more than 50,000 healthcare providers worldwide — and why they are the number one Doctor-Recommended Professional Supplement Brand.
- Produced in GMP and NSF-certified facilities
- 200,000+ quality tests annually from ingredient sourcing to finished product
- Third-party tested independently for purity, potency, and safety
- Non-GMO and gluten-free
- Vegetarian capsule
- Made by a registered B-Corp — ethically and sustainably produced
- Backed by a 60-Day Money-Back Guarantee
The Pharmacist's Perspective
At KHANG PHARMACY, we curate only what we would recommend to our own families. UltraFlora® Night Rest & Digest stands out because it addresses a gap most supplements ignore: the overnight window. While you rest, your body is in repair mode — and giving your gut the right tools during that time can make a meaningful difference in how you feel the next morning. If you have been chasing better sleep or struggling with recurring digestive discomfort, this may be the missing piece in your nighttime routine.
Shop UltraFlora® Night Rest & Digest Postbiotic — Try It Risk-Free →
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Based on IQVIA ProVoice Survey, 12 months ending September 2024.
